Gene screening of Wharton's jelly derived stem cells

Issue title: Papers from the 8th Scientific Meeting on Cartilage Engineering, September 2013, Nancy, France

Article type: Research Article

Authors: Mechiche Alami, S.^; | Velard, F.^; | Draux, F.^; | Siu Paredes, F.^; | Josse, J.^; | Lemaire, F.^; | Gangloff, S.C.^; | Graesslin, O. | Laurent-Maquin, D.^{; ;} | Kerdjoudj, H.^{; ;}

Affiliations: EA 4691 «Biomatériaux et Inflammation en Site Osseux», Pôle Santé, SFR CAP-Santé (FED 4231), Université de Reims Champagne-Ardenne, Reims, France | UFR D'odontologie, URCA, Reims, France | Centre de Biologie Moléculaire, Université d'Aréquipa, Aréquipa, Pérou | UFR de Pharmacie, URCA, Reims, France | Département de Gynécologie CHU de Reims, Reims, France | Département de Chirurgie Dentaire, CHU de Reims, Reims, France

Note: [] Address for correspondence: Dr. Halima Kerdjoudj, EA 4691 «Biomatériaux et Inflammation en Site Osseux», Pôle Santé, SFR Cap-Santé (FED 4231), Université de Reims Champagne-Ardenne, 51 Rue Cognacq Jay, 51095 Reims Cedex, France. Tel.: +33 3 26 91 80 12; Fax: +33 3 26 91 86 43; E-mail: [email protected]

Abstract: Stem cells are the most powerful candidate for the treatment of various diseases. Suitable stem cell source should be harvested with minimal invasive procedure, found in great quantity, and transplanted with no risk of immune response and tumor formation. Fetal derived stem cells have been introduced as an excellent alternative to adult and embryonic stem cells use, but unfortunately, their degree of “stemness” and molecular characterization is still unclear. Several studies have been performed deciphering whether fetal stem cells meet the needs of regenerative medicine. We believe that a transcriptomic screening of Wharton's jelly stem cells will bring insights on cell population features.

Keywords: PCR array, human Wharton's jelly stem cells, regenerative medicine

DOI: 10.3233/BME-140974

Journal: Bio-Medical Materials and Engineering, vol. 24, no. s1, pp. 53-61, 2014