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Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 2nd International Conference on Biomedical Engineering and Biotechnology, 11–13 October 2013, Wuhan, China
Article type: Research Article
Authors: Zeng, Hongjuan; ; ; | Wang, Deshun | Yu, Junsheng
Affiliations: School of Life Science and Technology, University of Electronic Science and Technology of China (UESTC), Jianshe Road, Chengdu 610054, PR China | School of Optoelectronic Information, University of Electronic Science and Technology of China (UESTC), Chengdu 610054, PR China
Note: [] This work was supported by National Natural Science Foundation of China (Grant No. 61071026).
Note: [] Corresponding author. [email protected]
Abstract: A layer of L-glycine-molecule-imprinted polyaniline (LMIP-PANI) polymer film has been modified on a carbon fiber electrode for the determination of L-glycine standard samples and L-glycine in cerebrospinal fluid of wistar mice. It has been found that a linear relationship exists between current and concentration for the glycine standard samples in the range of 0–12 μM by using the LMIP-PANI-modified carbon fiber electrode as a sensor. However, there is no any relationship between current and concentration for the carbon fiber electrode modified with no-glycine-molecule-imprinted polyaniline (NIP-PANI). The MIP-PANI- and NIP-PANI-modified carbon fiber films have been characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS) and electrochemistry methods. The investigation shows that the MIP-PANI-imprinted carbon fiber electrode will have a potential application in in-situ monitoring neurotransmitter due to its easy fabrication, low cost, bio-compatibility and flexibility.
Keywords: Glycine, polyaniline, imprint, film, cerebrospinal fluid
DOI: 10.3233/BME-130907
Journal: Bio-Medical Materials and Engineering, vol. 24, no. 1, pp. 1085-1091, 2014
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