Synthesis and Characterization of Poly(1,2-propanediol-co-1,8-octanediol-co-citrate) Biodegradable Elastomers for Tissue Engineering
Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 2nd International Conference on Biomedical Engineering and Biotechnology, 11–13 October 2013, Wuhan, China
Affiliations: Key Laboratory of Green Chemical Engineering and Technology of College of Heilongjiang Province, College of Chemical and Environmental Engineering, Harbin University of Science and Technology, Harbin 150040, China | Center for Biomedical Materials and Engineering, Harbin Engineering University, Harbin 150001, China
Abstract: In this paper, citric acid, 1,8-octanediol and 1,2-propanediol were used as reactive monomers to synthesize poly(1,2-propanediol-co-1,8-octanediol-co-citrate) (PPOC) elastomers by melt polycondensation. The PPOC elastomers were characterized by FTIR, 1H-NMR, thermal gravimetric analysis (TGA), differential scanning calorimetry (DSC), hydrophilic test and mechanical test. The results indicated that citric acid had reacted with 1,8-octanediol and 1,2-propanediol, respectively. The sol content, swelling degree and hydrophilicity of PPOC elastomers increased with the higher content of 1,2-propanediol, while the tensile strength and the thermal degradation temperature decreased. The results indicate the addition of 1,2-propanediol reduces the crosslinking density and the flexibility of PPOC elastomers.
