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Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 2nd International Conference on Biomedical Engineering and Biotechnology, 11–13 October 2013, Wuhan, China
Article type: Research Article
Authors: Pei, Bao-Qing; | Li, Hui | Li, De-Yu | Fan, Yu-Bo | Wang, Chuan | Wu, Shu-Qin
Affiliations: School of biological Science & Medical Engineering, Beihang University, Beijing, 100191, China | North University of China, Taiyuan, 030051, China
Note: [] Corresponding author, Bao-Qing Pei, Email: [email protected]
Abstract: The internal hydrostatic pressure (IHP) of the intervertebral disc is the functional and physiological basis of the spine. Disc bulging is a direct effect of increased IHP and can be used to evaluate the IHP without destroying the structure of the disc. Disc tissue engineering is a developing field but more data on the properties of normal discs are required for evaluation of possible graft materials. However, very little data is available concerning bulge distribution along the normal disc surface under creep. Methods: Fifteen motion segment specimens of ovine IVD were used to analyze axial creep, and disc bulging deformations of 5 markers on the surface were measured and analyzed. Findings: The maximum radial bulging rate was 2.78%±1.09% and the position at which the maximum radial deformation occurred was found to be below the midline of the disc during all levels of loading. The results showed that deformations occurred in the order vertical, radial, circumferential. Interpretation: Disc bulging during creep is a very important biomechanical response, affecting spinal functions. The deformation regularities of the disc surface were identified and may help supply important basic data for disc tissue engineering.
Keywords: Disc bulging, surface distribution deformation, compressive creep
DOI: 10.3233/BME-130799
Journal: Bio-Medical Materials and Engineering, vol. 24, no. 1, pp. 191-198, 2014
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