Affiliations: Department of Mechanical Engineering, The University of Memphis, Memphis, TN 38152, USA | Evans Central, Eden Prairie, MN 55344, USA
Note: [] Requests for reprints should be addressed to Dr. Gladius Lewis, Department of Mechanical Engineering, The University of Memphis, Memphis, TN 38152.
Abstract: Two surface analytical spectroscopic techniques (namely, angular-dependent X-ray photoelectron spectroscopy and static secondary ion mass spectrometry) were used to characterize the nature and composition of the surface and near-surface layers formed on three biomedical polymers (namely, low-density polyethylene, expanded polytetrafluoroethylene, and a silicone elastomer) when exposed to Factor Xa in a buffer solution under adsorption conditions. It is shown that the results extracted from the spectroscopic measurements are consistent with each other. The clinical significance of the results is discussed in terms of screening biomedical polymers for use in fabricating cardiovascular system components.
Keywords: X-ray photoelectron spectroscopy, secondary ion mass spectrometry, polymers, Factor Xa
