An analysis of frequency response for the blood flow of volume pulse in microcirculation

Article type: Research Article

Authors: Wang, Y. | Zhang, S. | Yang, Y.M. | Luo, Z.C. | Zhang, J.H. | Zeng, Y.J.

Affiliations: Biomedical Engineering Center, Beijing University of Technology, Beijing 100022, P.R. China

Note: [] Corresponding author: Y.J. Zeng, Biomedical Engineering Center, Beijing University of Technology, Beijing 100022, P.R. China. Tel.: +86 10 67391809, +86 10 67391685; Fax: +86 10 67391610; E‐mail: [email protected].

Abstract: In this paper, a frequency analysis for the microcirculation model is introduced to find new microcirculation parameters in the frequency domain. By using Bode Plot of transfer function, we found two characteristic parameters of the model: damping ratio ξ and break frequency ωn. By analyzing the variation of ξ and ωn, it enables us to have better understanding of different states of microcirculation. At low damping, 0<ξ<1, the state of microcirculation will be better and better along with the increasing of the ωn. At over damping, ξ≥1, the state of microcirculation will be worse and worse along with the descending of the ωn. The results of experiments on 120 subjects are consistent with the analytical results of the model.

Keywords: Frequency response, blood volume pulse, microcirculation, damping ratio, break frequency

Journal: Bio-Medical Materials and Engineering, vol. 15, no. 3, pp. 189-197, 2005