You are viewing a javascript disabled version of the site. Please enable Javascript for this site to function properly.
Go to headerGo to navigationGo to searchGo to contentsGo to footer
In content section. Select this link to jump to navigation

Preparation of polysaccharide loaded collagen membrane with anti-oxidative activity

Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 4th International Conference on Biomedical Engineering and Biotechnology, 18–21 August 2015, Shanghai, China

Guest editors: Feng Liu, Dong-Hoon Lee, Ricardo Lagoa and Sandeep Kumar

Article type: Research Article

Authors: Shu, Zibin | Ding, Shengli | He, Xiaohong | Dai, Xuemei | Xiao, Qian | Yang, Min | Leng, Xue | Ma, Yanshun; * | Yang, Hua; *

Affiliations: College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, Sichuan 610066, China

Correspondence: [*] Address for correspondence: Yanshun Ma, College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, Sichuan 610066, China. Tel.: 0086-028-84760802; Fax: 0086-028-84766101; E-mail: [email protected]. Hua Yang, College of Chemistry and Materials Science, Sichuan Normal University, Chengdu, Sichuan 610066, China. Tel.: 0086-028-84760802; Fax: 0086-028-84766101; E-mail: [email protected].

Keywords: Collagen, lycium barbarum polysaccharides, anti-oxidative, drug release, membrane

DOI: 10.3233/BME-151292

Journal: Bio-Medical Materials and Engineering, vol. 26, no. s1, pp. S81-S87, 2015

Published: 2015
Get PDF open access

The scavenging activity of polysaccharides from Lycium barbarum, Lentinus edodes and Ganoderma Lucidum Karst to DPPH free radicals was investigated. It was found that among the three polysaccharides, Lycium barbarum polysaccharides (LBP) exhibits the best scavenging activity. Polysaccharide loaded collagen membranes were prepared by mixing LBP with collagen, starch, glycerol, sodium carboxymethyl cellulose and glutaraldehyde. In vitro drug release from membranes was evaluated. With increasing the immersion time, the release rate first increases and then slows down. Meanwhile, the scavenging activity to DPPH radicals exhibits similar variation, in agreement with a good release effect of the membrane. The optimal formulation of collagen membrane and preparation parameters were obtained considering the overall properties and the scavenging activity to radicals.

Show more