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Experimental verification of depolarization effects in bioelectrical impedance measurement

Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 3rd International Conference on Biomedical Engineering and Biotechnology, 25–28 September 2014, Beijing, China

Article type: Research Article

Authors: Chen, Xiaoyan; | Lv, Xinqiang | Du, Meng

Affiliations: College of Electronic Information and Automation, Tianjin University of Science and Technology, Tianjin 300222, China

Note: [] Corresponding author: Xiaoyan Chen, College of Electronic Information and Automation, Tianjin University of Science and Technology, Tianjin 300222, China. Tel.: 13752113103; Fax: (86)22-60275497; E-mail: [email protected].

Keywords: Electrode polarization, depolarization correction, impedance measurement, low-frequency

DOI: 10.3233/BME-141195

Journal: Bio-Medical Materials and Engineering, vol. 24, no. 6, pp. 3675-3683, 2014

Published: 2014
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Abstract

The electrode polarization effects on bioelectrical impedance measurement at low-frequency cannot be ignored. In this paper, the bioelectrical data of mice livers are measured to specify the polarization effects on the bio-impedance measurement data. We firstly introduce the measurement system and methodology. Using the depolarization method, the corrected results are obtained. Besides, the specific effects of electrode polarization on bio-impedance measurement results are investigated using comparative analysis of the previous and posterior correction results from dielectric spectroscopy, Cole-Cole plot, conductivity and spectroscopy of dissipation tangent. Experimental results show that electrode polarization has a significant influence on the characteristic parameters of mouse liver tissues. To be specific, we see a low-frequency limit resistance R0 increase by 19.29%, a reactance peak XP increase by 8.50%, a low-frequency limit conductivity Kl decrease by 17.65% and a dissipation peak tangent decrease by 160%.

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