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Development of visible and NIR imaging equipment for small animals with smart pad

Issue title: Frontiers in Biomedical Engineering and Biotechnology – Proceedings of the 3rd International Conference on Biomedical Engineering and Biotechnology, 25–28 September 2014, Beijing, China

Article type: Research Article

Authors: Eum, Nyeon Sik | Han, Jung Hyun | Seong, Ki Woong | Lee, Jong Ha | Park, Hee Joon;

Affiliations: U-BioMed Inc., B. I. Center, Kyungpook National University, 80 Daehak-ro, Buk-Gu, Daegu, 704-701, Korea | Department of Biomedical Engineering, Kyungpook National University Hospital, 130 Dongdeok-ro, Jung-Gu, Daegu, 704-712, Korea | Department of Biomedical Engineering, Keimyung University, 1095 Dalgubeoldae-ro, Dalseo-Gu, Daegu, 702-701, Korea

Note: [] Corresponding author: Hee Joon Park, Department of Biomedical Engineering, Keimyung University, 1095 Dalgubeoldae-ro, Dalseo-Gu, Daegu, 702-701, Korea. Tel.: +82-53-580-3731. E-mail: [email protected].

Keywords: Visible/NIR image, animal imaging, fluorescence, mobile-based, merged image

DOI: 10.3233/BME-141124

Journal: Bio-Medical Materials and Engineering, vol. 24, no. 6, pp. 3033-3041, 2014

Published: 2014
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Abstract

The portable visible and near-infrared (NIR) imaging equipment for a pre-clinical test with small animals was designed and developed in this paper. The developed equipment is composed of a CCD camera, a focusing lens, an objective lens, a NIR band pass filter and a NIR filter driving motor. An NIR ray is mainly used for imaging equipment because it has high light penetration depth in biological tissue. Therefore, NIR fluorescent agents are available for chemical conjugation to targeting molecules in vivo. This equipment can provide a visible image, NIR image and merged image simultaneously. A communication system was specifically established to check obtained images through a smart pad in real time. It is less dependent on space and time than the conventional system.

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