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Price: EUR 185.00Authors: Copley, Alfred L.
Article Type: Correction
DOI: 10.3233/CH-1986-6210
Citation: Clinical Hemorheology and Microcirculation, vol. 6, no. 2, pp. 165-165, 1986
Authors: Heinen, A. | Brunner, R. | Hossmann, V.
Article Type: Research Article
Abstract: The influence of different molecular weight dextrans (MW: 6000, 10 000, 40 000, 70 000), hydroxyethyl starch, gelatine and albumin on plasma viscosity, apparent whole blood viscosity and erythrocyte flexibility was studied in vitro. Compared to blood samples two hours incubated with Ringers solution alone, dextrans of 40 000 and 70 000 molecular weight caused the most pronounced increase in plasma viscosity, erythrocyte aggregation and decrease in erythrocyte flexibility. For albumin, hydroxyethyl starch and gelatine these effects were less, but still significant in comparison to the control measurements. The commercially available dextran solutions for clinical use vary widely with …respect to their molecular weight (MW distribution: > 90% of the total amount within the range of 10 000–80 000). It has also been demonstrated, that the high molecular weight components are excreted at a lower rate, which leads to an increase of plasma concentration during repeated infusions (ARTURSON 1954, (1)). The results of our in vitro study support the hypothesis that the increase in apparent whole blood viscosity after repeated infusions, as demonstrated in several clinical experiments is due to an increase of higher molecular weight components, which accumulate in plasma during prolonged infusions with LMWD. Show more
Keywords: erythrocyte flexibility, erythrocyte aggregation, plasma viscosity, whole blood viscosity, high molecular weight dextrans
DOI: 10.3233/CH-1986-6211
Citation: Clinical Hemorheology and Microcirculation, vol. 6, no. 2, pp. 167-173, 1986
Authors: Forconi, S. | Rossi, C. | Guerrini, M. | Cappelli, R. | Materazzi, M. | Pieragalli, D. | Pecchi, S. | Acciavatti, A. | Galigani, C. | Di Perri, T.
Article Type: Research Article
Abstract: We have studied the acute effects of smoking two cigarettes with a high nicotine content in young healthy smokers. The haemorheological profile (blood and plasma viscosity and blood filterability), the peripheral haemodynamics (blood flow in the limbs, at rest and during reactive postischemic hyperemia using a strain gauge plethysmograph) and the metabolic pattern (acid-base balance, oxymetric values and COHb) have been evaluated before and after smoking. Results have shown that cigarette smoking provokes besides an evident increase of COHb, a decrease of blood filterability and an impairment of the last phase of the reactive hyperemia with the lenghtening of the …total time. These data suggest that a possible impairment of the blood flow at microcirculatory level can occur in these subjects after cigarette smoking. Show more
Keywords: smoking, blood rheology, peripheral haemodynamics, microcirculation
DOI: 10.3233/CH-1986-6212
Citation: Clinical Hemorheology and Microcirculation, vol. 6, no. 2, pp. 175-184, 1986
Authors: Mitchell, James E. | Zuckerman, Leon | Vagher, J. Paul | Holloway, D. Scott | Caprini, Joseph A.
Article Type: Research Article
Abstract: The viscoelastic behavior of coagulating plasma and whole blood were examined in a modified thrombelastograph. We found that platelets greatly increased the measured rigidity of coagulating blood and plasma, and this rigidity was augmented by erythrocytes. Red cells also slowed the rate of stiffening, which may be due to the red cell membrane activity. In whole blood, the relaxation of stress at constant strain demonstrated a biphasic pattern: the early rapid phase depended on the primary orientation of fibrin into a network by platelets and red cells. The second slower phase was dependent on Factor XIII activity in secondary rearrangement …of the network. Crosslinking of fibrin by Factor XIII had little effect on rigidity. Show more
Keywords: Viscoelasticity, Blood Coagulation
DOI: 10.3233/CH-1986-6213
Citation: Clinical Hemorheology and Microcirculation, vol. 6, no. 2, pp. 185-194, 1986
Authors: Palareti, G. | Poggi, M. | Tricarico, M.G. | Torricelli, P. | Cavazzuti, F. | Coccheri, S.
Article Type: Short Communication
Keywords: high altitude, haemorheology, haematocrit, plasma viscosity, red cell filterability
DOI: 10.3233/CH-1986-6214
Citation: Clinical Hemorheology and Microcirculation, vol. 6, no. 2, pp. 195-199, 1986
Authors: Liao, Fu-long
Article Type: Letter
DOI: 10.3233/CH-1986-6215
Citation: Clinical Hemorheology and Microcirculation, vol. 6, no. 2, pp. 201-201, 1986
Authors: Benner, Klaus-U. | Nordt, Frank J.
Article Type: Abstract
DOI: 10.3233/CH-1986-6216
Citation: Clinical Hemorheology and Microcirculation, vol. 6, no. 2, pp. 203-203, 1986
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