Clinical Hemorheology and Microcirculation - Volume 5, issue 5
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Impact Factor 2019: 1.642
Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research.
The endeavour of the Editors-in-Chief and publishers of
Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of
Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process.
Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.
The following professionals and institutions will benefit most from subscribing to
Clinical Hemorheology and Microcirculation: medical practitioners in all fields including hematology, cardiology, geriatrics, angiology, surgery, obstetrics and gynecology, ophthalmology, otology, and neurology. Pharmacologists, clinical laboratories, blood transfusion centres, manufacturing firms producing diagnostic instruments, and the pharmaceutical industry will also benefit.
Important new topics will increasingly claim more pages of
Clinical Hemorheology and Microcirculation: the role of hemorheological and microcirculatory disturbances for epidemiology and prognosis, in particular regarding cardiovascular disorders, as well as its significance in the field of geriatrics. Authors and readers are invited to contact the editors for specific information or to make suggestions.
Abstract: At atmospheric pO2 and at 25°C the red blood cell rigidity is highly increased in sickle cell syndromes (SS and AS) and in β thalassemia (minor and intermedia). The initial filtration flow rate of RBCs was evaluated with the hemorheometre. The individual transit time of cells passing through 5 μ pores was measured with a new apparatus the “cell transit time analyser” which permitted the study of up to 1000 cells in one minute. This method showed the heterogeneity of normal and sickle cell.s at atmospheric pO2 .
Keywords: Deformability, Hemoglobinopathy, transit time, Red Blood Cells
Abstract: The aim of this study is to compare 3 methods allowing to assess R.B.C. Aggregation: steady viscometry, unsteady viscometry ana light reflectometry. This comparison was performed on blood samples drawn from forty insulino-dependent diabetics. We found strong correlations between the parameters measured by the three techniques. These correlations are most likely explained by the existence of a common underlying parameter influencing the three types of measurements: the adhesive energy per unit area. Moreover, we attempted to know whether the measured viscometric or light reflectometric parameters are good diagnosis (or prognosis) instruments. For that we compared the number of diabetics…having an abnormal value of the different aggregometric parameters. The thixotropy index, measured by unsteady viscometry, and the disagregation shear stress reached by light reflectometry detected the largest number of pathological cases. The steady viscometric data were then discussed with regard to the conditions of appearance of a plasma layer near the viscometer walls.