Affiliations: Department of Bionanosystem Engineering, Chonbuk National University, Jeonju, Jeonbuk, Korea | Division of Mechanical Design Engineering, Chonbuk National University, Jeonju, Jeonbuk, Korea | Department of Bioengineering, North Carolina A&T State University, Greensboro, NC, USA
Note: [] Address for correspondence: C.S. Kim, Division of Mechanical Design Engineering, Chonbuk National University, Jeonju, Jeonbuk 561-756, Korea. Tel.: +82 63 270 4284; Fax: +82 63 270 2460; E-mail: [email protected].
Abstract: This article describes a preliminary investigation and prototype fabrication of a novel potential sensing method to continuously monitor vascular stent fractures. A potential measurement system consisting of Wheatstone bridge circuit and signal conditioning circuit was designed for the cardiovascular stent durability and fatigue test. Each end of a bare and polyurethane-covered Nitinol vascular stent was electrically connected to the potential measurement system and then immersed either in simulated body fluid (SBF) media or distilled water at 36.4±1°C. When the stent experienced fracture (i.e., a cut), its electrical potential decreased with an increase in electrical resistance. This method successfully measured fractures in the stent regardless of location. Furthermore, the number of cycles at the onset of stent fracture was accurately detected and continuously monitored using this technique. Thus, the present fracture detection method, which to our knowledge is the first ever report to use electrical potential measurement for stent durability test, gives a fast, real-time, accurate and efficient detection of fractures in stent during in vitro fatigue and durability test.
