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Article type: Research Article
Authors: Jahed, Mahsaa; | Ghalichi, Farzana | Farhoudi, Mehdib
Affiliations: [a] Biomedical Engineering Department, Division of Biomechanics, Sahand University of Technology, Tabriz, Iran | [b] Neurosciences Research Center, Tabriz University of Medical Science, Tabriz, Iran
Correspondence: [*] Corresponding author. E-mail: [email protected]
Abstract: BACKGROUND:The development of any disturbance in the Circle of Willis (COW) can change the hemodynamics of blood flow and result in damage to the vascular system. Clinical methods such as TCD for diagnosing an aneurysm or growth factors and rupture can measure blood velocity. Several factors influence the accuracy of TCD that can lead to wrong evaluations and affect the treatment planning. OBJECTIVE:In this study, the conformity between CFD and TCD was accomplished for investigating the accuracy of the clinical method (TCD) in different vessels of the Circle of Willis. METHODS:The realistic three-dimensional models have been produced from angiography images. Considering fluid-structure interaction, a domain of the blood flow and vessel wall has been simulated by the ANSYS.CFX software. The velocity in the cerebral arteries has been calculated and compared with the velocity acquired from TCD. RESULTS:According to the findings, there were significant differences between the results obtained from computational fluid dynamics and Doppler test in different vessels of the Circle of Willis. In some areas, differences close to 80 cm/s were also reported. CONCLUSION:According to the results, there are possibilities of errors in carrying out a Doppler test in some arteries and can lead to wrong estimates and ultimately incorrect decisions.
Keywords: Aneurysm, blood velocity, cerebral arteries, Transcranial Doppler, computational fluid dynamics
DOI: 10.3233/BME-191064
Journal: Bio-Medical Materials and Engineering, vol. 30, no. 4, pp. 427-438, 2019
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