Biomechanical evaluation of four surgical scenarios of lumbar fusion with hyperlordotic interbody cage: A finite element study

Article type: Research Article

Authors: Zhang, Zhenjun^{a; b} | Fogel, Guy R.^c | Liao, Zhenhua^b | Sun, Yitao^d | Sun, Xuejun^e | Liu, Weiqiang^{a; b;}

Affiliations: [a] Department of Mechanical Engineering, Tsinghua University, Beijing, China | [b] Biomechanics and Biotechnology Lab, Research Institute of Tsinghua University in Shenzhen, Shenzhen, China | [c] Spine Pain Begone Clinic, San Antonio, TX, USA | [d] Haicheng City Central Hospital, Haicheng, China | [e] Beijing Yingnuanlihe Technologies Co., Ltd, Beijing, China

Correspondence: [*] Corresponding author: Weiqiang Liu, Tsinghua University, Haidian District, Beijing, China. Tel.: +86 0755 26551376; Fax: +86 0755 26551380; E-mail: [email protected]

Abstract: BACKGROUND:Lumbar spinal fusion in the interbody space is augmented with interbody fusion cages to provide structural support while arthrodesis occurs. Subsidence is a serious complication of interbody fusion. However, the biomechanical influence of anterior longitudinal ligament (ALL) and pedicle screws on subsidence has not been fully understood. OBJECTIVE:To investigate biomechanical effects of the hyperlordotic cages in different surgical conditions using finite element analysis. METHODS:Four surgical finite element (FE) models were constructed by inserting 15 degree lordosis cage at the L3-L4 disc space. The four surgical conditions were ALL intact (M1), ALL resected (M2), ALL intact and bilateral pedicle screws (M3), and ALL resected and bilateral pedicle screws (M4). Follow loads were applied at the L2 vertebral body while the inferior surface of L5 was fixed. FEA was implemented to simulate the four motion modes and biomechanical properties of four fusion scenarios with hyperlordotic interbody cage were compared. RESULTS:The range of motion (ROM) and facet joint force (FJF) at L3-L4 decreased significantly after fusion during all the motion modes. The cage stress and endplate stress at L3-L4 increased significantly after fusion during all the motion modes. The cage stress and endplate stress at L3-L4 for M3 and M4 were smaller than that for M1 and M2 during all the motion modes. The FJF at L3-L4 for M3 and M4 were smaller than that for M1 and M2 during extension, bending, and rotation. CONCLUSIONS:ALL has little effect on the biomechanics after lumbar fusion with hyperlordotic interbody cage. The bilateral pedicle screws significantly decreased the stress in cage, stress in endplate at L3-L4, and lowered facet contact force except for flexion mode. The implication is that the supplemental bilateral pedicle screws are recommended whether or not the ALL is resected.

Keywords: Lumbar spine, biomechanics, lumbar fusion, hyperlordotic interbody cage, finite element analysis (FEA), bilateral pedicle screws, anterior longitudinal ligament (ALL), range of motion (ROM), subsidence, facet contact force

DOI: 10.3233/BME-181004

Journal: Bio-Medical Materials and Engineering, vol. 29, no. 4, pp. 485-497, 2018