Hemorheologic factors and post renal transplant complications

Article type: Research Article

Authors: Berling, C. | Lacombe, C. | Lelievre, J.C.

Affiliations: Unité de Biorhéologie, Dpt de Biophysique, CHU Pitié-Salpêtrière, 91, bd de l’Hôpital, 75013 Paris, France

Note: [] Accepted by: Editor A.M. Ehrly

Abstract: An hemorheological investigation is performed on renal transplant patients whose graft function was normal and who suffered for the most from erythrocytosis. The aim of this work is to evaluate the hemorheological state of those patients and to show up the possible relationship between viscometric data and post-transplant complications. Blood rheological study is performed using a Couette viscometer. Unsteady flow measurements related to the blood viscoelasticity and thixotropy are recorded, so that measurements in steady flow conditions related to the shear-thinning of blood. The rheological properties of blood are shown to be strongly related to the clinical progress of the patients. The main result is a relationship between important post-transplant complications and a pathological erythrocyte disaggregability.

Keywords: hemorheology, renal transplantation, erythrocytosis, blood viscosity, red blood cell aggregation

DOI: 10.3233/CH-1987-7507

Journal: Clinical Hemorheology and Microcirculation, vol. 7, no. 5, pp. 707-713, 1987