Blood rheological abnormalities in the microcirculation during experimental traumatic shock

Issue title: Selected proceedings of the 12th European Conference on Clinical Hemorheology, 22‐26 June 2003, Sofia, Bulgaria

Article type: Research Article

Authors: Tatarishvili, J. | Momtselidze, N. | Mchedlishvili, G.

Affiliations: Microcirculation Research Center, I.Beritashvili Institute of Physiology, 14 Gotua St., 0160 Tbilisi, Georgia

Note: [] Corresponding author. E‐mail: [email protected].

Abstract: Objective: To find whether the principal indices of blood rheological disorders related to the microcirculation undergo drastic changes during the traumatic shock. Methods: RBC aggregability and deformability, as well as the systemic hematocrit, were assessed in white laboratory rats with the techniques that provided us with direct and quantitative data. Results: We found that in the experimental animals the RBC aggregability was sharply increased, the RBC deformability significantly decreased, while the systemic hematocrit underwent considerable lowering during the traumatic shock. Conclusion: The blood rheological properties are significantly disordered during development of the traumatic shock.

Keywords: Microcirculation, blood rheological disorders, experimental traumatic shock

Journal: Clinical Hemorheology and Microcirculation, vol. 30, no. 3-4, pp. 407-410, 2004