Long term follow-up after endovascular brachytherapy of femoro-popliteal arteries

Issue title: Selected Presentations held at the 34th Conference of the German Society for Clinical Microcirculation and Hemorheology, Regensburg, Germany, 27–28 November, 2015

Guest editors: L. Prantl, E.M. Jung and F. Jung

Article type: Research Article

Authors: Thalhammer, Christoph^{a; *} | Alvarez, Elena^a | Husmann, Marc^a | Staub, Daniel^b | Kaspar, Mathias^b | Aschwanden, Markus^b | Amann-Vesti, Beatrice R.^a

Affiliations: [a] University Hospital Zurich, Clinic for Angiology and University Zurich, Zurich, Switzerland | [b] University Hospital Basel, Clinic for Angiology Basel, Switzerland

Correspondence: [*] Corresponding author: Christoph Thalhammer, MD, University Hospital Zurich, Clinic for Angiology, Rämistrasse 100, CH-8091 Zurich, Switzerland. Tel.: +41 44 255 2671; Fax: +41 44 255 4510; E-mail: [email protected]

Abstract: To perform a long term follow-up after endovascular brachytherapy (EVBT) and balloon angioplasty (PTA) regarding vessel patency and diameter. EVBT had been successfully used to decrease restenosis in short term, but long term data are lacking. Participants of a randomized study comparing EVBT and balloon angioplasty alone were invited for follow-up examination ten years after intervention. Using a standardized protocol measurement of the patency and vessel diameter was performed of femoral and popliteal arteries. 44 patients were included, 21 had been treated with EVBT and 23 had received PTA alone. Target lesion patency was similar between the two groups (90.5% vs. 87.0%). Vessel diameter of the target lesion was significantly greater in the EVBT group (6.4 mm, range 3.9–9.9) compared to the controls (5.0 mm, range 3.1–7.4; p = 0.002). Ten years after EVBT of femoro-popliteal arteries vessel diameter is significantly increased whereas patency rate is not different compared to angioplasty alone.

Keywords: Endovascular brachytherapy, femoro-popliteal artery, long term follow-up, duplex sonography, peripheral artery disease, aneurysm

DOI: 10.3233/CH-151997

Journal: Clinical Hemorheology and Microcirculation, vol. 61, no. 2, pp. 251-257, 2015