Searching for just a few words should be enough to get started. If you need to make more complex queries, use the tips below to guide you.
Article type: Research Article
Authors: Eterović, D. | Pintarić, I. | Tocilj, J. | Reiner, Z.
Affiliations: Department of Nuclear Medicine (author responsible for correspondence and reprints), Clinical Hospital Split, Spinciceva 1, 58 000 Split, Croatia | Department of Neurology, Clinical Hospital Split, Spinciceva 1, 58 000 Split, Croatia | Department of Pulmonary Medicine, Clinical Hospital Split, Spinciceva 1, 58 000 Split, Croatia | Department of Patophysiology, Clinical Hospital Rebro, Zagreb, Croatia
Abstract: The aim of the study was to assess the separate influences of plasma lipoproteins and fibrinogen on plasma viscosity (PV), minimizing/controlling for the effect of confounders by patient selection and by data analysis. In 30 normal male volunteers, nonsmokers, and 90 male, nonobese nonsmokers with various types of primary hyper lipoproteinemias, but otherwise healthy, the plasma levels of total cholesterol (Chol), the low density cholesterol (LDL) , the high density cholesterol (HDL) , triglyceride. (Tg) and fibrinogen (Fib) were measured in conjunction with determinations of plasma viscosity (PV). By the stepwise regression variable selection 60% of variation in PV was explained by equating PV as: PV(mPa·s) = 1.352 + 0.0167·Chol(mmol/L) + 0.0285·Fib(g/L) + 0.0054·Tg(mmoljL) + 0.00318·Hematocrit(%) - 0.030·HDL(mmol/L), R=0.774. Expressed in standardized residuals the effect of Chol was about 3 times greater compared to Fib and Tg. Thus, in the studied sample the leading influence of cholesterol on plasma viscosity was observed, whereas hematocrit and HDL exerted independent positive and negative associations with plasma viscosity, respectively.
Keywords: Primary hypercholesterolemia, primary hypertriglyceridemia, blood rheology, fibrinogen, hematocrit
DOI: 10.3233/CH-1995-15605
Journal: Clinical Hemorheology and Microcirculation, vol. 15, no. 6, pp. 841-850, 1995
IOS Press, Inc.
6751 Tepper Drive
Clifton, VA 20124
USA
Tel: +1 703 830 6300
Fax: +1 703 830 2300
[email protected]
For editorial issues, like the status of your submitted paper or proposals, write to [email protected]
IOS Press
Nieuwe Hemweg 6B
1013 BG Amsterdam
The Netherlands
Tel: +31 20 688 3355
Fax: +31 20 687 0091
[email protected]
For editorial issues, permissions, book requests, submissions and proceedings, contact the Amsterdam office [email protected]
Inspirees International (China Office)
Ciyunsi Beili 207(CapitaLand), Bld 1, 7-901
100025, Beijing
China
Free service line: 400 661 8717
Fax: +86 10 8446 7947
[email protected]
For editorial issues, like the status of your submitted paper or proposals, write to [email protected]
如果您在出版方面需要帮助或有任何建, 件至: [email protected]