Affiliations: Department of Vascular Insufficiency, Collegium Medicum of Jagiellonian University, Cracow, Poland | Department of Motoral Rehabilitation, Academy of Physical Education, Cracow, Poland | Laboratory of Clinical Hemorheology, Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Note: [] Corresponding author: Prof. Dr. Z. Dąbrowski, Department of Motoral Rehabilitation, Academy of Physical Education, Al. Jana Pawła II 78, 31-571 Cracow, Poland. E-mail: [email protected].
Abstract: Rheological studies concerning aggregation and elongation of erythrocytes were carried out in 21 patients (mean age 56 years) with chronic venous disease (CVD) and 10 (mean age 45 years) healthy control subjects, with the use of a LORCA device. Higher values of parameters characterizing both erythrocyte elongation (EI) and aggregation (γthr) in non-control patients than in the control group were found. These values differed significantly ranging from 1.13 to 8.23 Pa for the shear stress and γthr in patients – 432.14, in relation to the control group – 166.5. It was proposed, that the increase in deformability may constitute a compensatory mechanism in subjects with chronic venous disease, due to increased resistance in their microcirculation.
