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Price: EUR 185.00Authors: Ajmani, R. | Puniyani, R.R. | Jaiswal, V.S.
Article Type: Research Article
Abstract: Hemorheological and biochemical investigations were performed in 274 patients with hypertension. Whole blood viscosity was measured at 8 different shear rates and was categorized as per individual's blood group. Plasma viscosity, red cell rigidity, platelet aggregation, erythrocyte sedimentation rate, hematocrit, fibrinogen, and serum triglyceride were also studied. We have found that in case of blood group “O” increase in the whole blood viscosity was maximum while in blood group “B” it was minimum. There was no significant difference in the plasma viscosity among different blood group. It shows that red blood cell is one of the major contributing factor for …change in whole blood viscosity. This change in the whole blood viscosity among different blood groups could be due to difference in the charge density of different blood groups and/or particular blood group is more susceptible for change in the blood viscosity. When whole blood viscosity, plasma viscosity, red cell rigidity, fibrinogen and triglyceride parameters were compared with normal controls, they were found to be significantly elevated. There was no significant difference in hematocrit and platelet aggregation. Show more
Keywords: Antigens, Blood Groups, Blood Viscosity, Hypertension
DOI: 10.3233/CH-1992-12411
Citation: Clinical Hemorheology and Microcirculation, vol. 12, no. 4, pp. 579-586, 1992
Authors: Sabio, Hernan | McKie, Virgil C.
Article Type: Research Article
Abstract: The erythrocyte sedimentation rate (ESR) is a non-specific laboratory test that is widely used by clinicians in their assessment of a disease state. The phenomenon of erythrocyte sedimentation is largely dependent on the concentration of plasma proteins and their interactions with erythrocyte surfaces. The use of the ESR in sickle cell anemia is impaired by the abnormal deformability of sickled cells. In an attempt to bypass this phenomenon, a mixed erythrocyte sedimentation rate (M-ESR) has been developed. In the M-ESR the pathological erythrocytes of sickle cell anemia are substituted for normal erythrocytes. Although less than 60% of symptomatic patients with …sickle cell anemia had an elevated ESR, 100% had an elevated M-ESR. Show more
Keywords: anemia, erythrocyte, hemoglobin sedimentation, sickle cell
DOI: 10.3233/CH-1992-12412
Citation: Clinical Hemorheology and Microcirculation, vol. 12, no. 4, pp. 587-592, 1992
Authors: Min, Huang Yi | Wei, Zhong | Quan, Qian Min | Rong, Zhou
Article Type: Research Article
Abstract: A three–week investigation was carried out on hemorheological and coagulative indices in rats exposed to carbon monoxide (CO). Results showed that in CO group, clotting times (tG″,tG′) were prolonged with lowered viscous modulus G″ and elastic modulus G′ of thrombus at thirty minute coagulation as well as platelet count (BP). However, hematocrit (Hct) and blood viscosity (BV) in this group were significantly increased. No difference in plasma viscosity (PV) was found between two groups. A correlation was established for the parameters, namely, G′=173.6+100.3PV−5.1Hct−6.6tG′. On the contrary, no alteration in Hct, G″, G′, platelet aggregation activity, clotting time of plasma was …found for blood exposed to CO in vitro. But it confirmed there was a strong negative correlation between Hct and G″ (r=−0.938), and G′ (r=−0.974) respectively. These results suggest that: (1) Carbon monoxide does not directly result in changes in thrombotic activity, but it can stimulate the growth of red blood cell by hypoxemia, (2) High Hct is responsible for the reduction of G″ and G′ in CO group. Show more
Keywords: Hemorheology, viscoelasticity, thrombus, carbon monoxide
DOI: 10.3233/CH-1992-12413
Citation: Clinical Hemorheology and Microcirculation, vol. 12, no. 4, pp. 593-598, 1992
Article Type: Other
DOI: 10.3233/CH-1992-12414
Citation: Clinical Hemorheology and Microcirculation, vol. 12, no. 4, pp. 599-623, 1992
Article Type: Other
DOI: 10.3233/CH-1992-12415
Citation: Clinical Hemorheology and Microcirculation, vol. 12, no. 4, pp. 625-625, 1992
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