Clinical Hemorheology and Microcirculation - Volume 12, issue 1
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Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research.
The endeavour of the Editors-in-Chief and publishers of
Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of
Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process.
Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.
The following professionals and institutions will benefit most from subscribing to
Clinical Hemorheology and Microcirculation: medical practitioners in all fields including hematology, cardiology, geriatrics, angiology, surgery, obstetrics and gynecology, ophthalmology, otology, and neurology. Pharmacologists, clinical laboratories, blood transfusion centres, manufacturing firms producing diagnostic instruments, and the pharmaceutical industry will also benefit.
Important new topics will increasingly claim more pages of
Clinical Hemorheology and Microcirculation: the role of hemorheological and microcirculatory disturbances for epidemiology and prognosis, in particular regarding cardiovascular disorders, as well as its significance in the field of geriatrics. Authors and readers are invited to contact the editors for specific information or to make suggestions.
Abstract: The haemodynamic disturbances which may exist downstream of a constriction have been implicated in the poor performance of small diameter prostheses which have a high rate of occlusion by thrombus formation at or near the anastomoses to the host vessels. Because the presence of turbulence in blood flows can be detrimental to the blood elements, factors which reduce or eliminate turbulence at these sites should be considered. This study forms part of an ongoing investigation into the role of wall compliance and vessel geometry on the development of post-stenotic flow disturbances in arterial prostheses and arterial reconstructions. The prostheses were…fabricated with two degrees of compliance corresponding roughly to that of a ‘rigid’ knitted Dacron prosthesis and that of a naturally-compliant peripheral vessel (femoral artery). Flow disturbances were measured in both cylindrical and 0.75° tapered prostheses using a 20 MHz rangegated ultrasound Doppler velocimeter. The instantaneous centreline velocity (from which the disturbance intensities were calculated) was measured in steady flow downstream of 50% and 75% stenoses which were positioned, in turn, at the inlet to each conduit as a model of a proximal anastomosis. Experimental data obtained at physiological Reynolds numbers between 375 and 1500 showed that the flow disturbance intensity measured in the compliant prostheses was always greater than in the corresponding rigid conduits – a surprising result as it has been shown that a compliant wall can delay the onset of turbulent flow in cylindrical tubes. In contrast, the magnitude of poststenotic flow disturbances measured in the tapered prostheses was significantly lower for both rigid and compliant systems when compared with the data for the cylindrical conduits.