Clinical Hemorheology and Microcirculation - Volume 1, issue 3
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Clinical Hemorheology and Microcirculation, a peer-reviewed international scientific journal, serves as an aid to understanding the flow properties of blood and the relationship to normal and abnormal physiology. The rapidly expanding science of hemorheology concerns blood, its components and the blood vessels with which blood interacts. It includes perihemorheology, i.e., the rheology of fluid and structures in the perivascular and interstitial spaces as well as the lymphatic system. The clinical aspects include pathogenesis, symptomatology and diagnostic methods, and the fields of prophylaxis and therapy in all branches of medicine and surgery, pharmacology and drug research.
The endeavour of the Editors-in-Chief and publishers of
Clinical Hemorheology and Microcirculation is to bring together contributions from those working in various fields related to blood flow all over the world. The editors of
Clinical Hemorheology and Microcirculation are from those countries in Europe, Asia, Australia and America where appreciable work in clinical hemorheology and microcirculation is being carried out. Each editor takes responsibility to decide on the acceptance of a manuscript. He is required to have the manuscript appraised by two referees and may be one of them himself. The executive editorial office, to which the manuscripts have been submitted, is responsible for rapid handling of the reviewing process.
Clinical Hemorheology and Microcirculation accepts original papers, brief communications, mini-reports and letters to the Editors-in-Chief. Review articles, providing general views and new insights into related subjects, are regularly invited by the Editors-in-Chief. Proceedings of international and national conferences on clinical hemorheology (in original form or as abstracts) complete the range of editorial features.
The following professionals and institutions will benefit most from subscribing to
Clinical Hemorheology and Microcirculation: medical practitioners in all fields including hematology, cardiology, geriatrics, angiology, surgery, obstetrics and gynecology, ophthalmology, otology, and neurology. Pharmacologists, clinical laboratories, blood transfusion centres, manufacturing firms producing diagnostic instruments, and the pharmaceutical industry will also benefit.
Important new topics will increasingly claim more pages of
Clinical Hemorheology and Microcirculation: the role of hemorheological and microcirculatory disturbances for epidemiology and prognosis, in particular regarding cardiovascular disorders, as well as its significance in the field of geriatrics. Authors and readers are invited to contact the editors for specific information or to make suggestions.
Abstract: The authors examine a study on the possible changes in blood and plasma viscosity in a group of hyperlipoproteinemic subjects. The study was carried out on 45 patients suffering from type IIA, IIB or IV moderate primary hyperlipoproteinemia. The control population was made up of a group of 71 male and female subjects with no glucid or lipid metabolism disorders. Rheological measurements were carried out by means of a Couette type coaxial cylinder viscometer. Concurrently, certain biochemical parameters such as glycemia, total cholesterol and triglycerides were measured on each individual patient. The results reveal an increase in blood and plasma…viscosity in all three types of patient. The authors discuss the results observed with reference to the lipid disturbances.
Abstract: Regular haemodialysis in eight patients using hollow fiber dialysers had no significant effect on clot retraction, platelet volume or platelet number. The observed low or subnormal values of platelet number, platelet volume and clot retraction in the whole group would seem to be a secondary, long-term effect of dialysis.
Abstract: The flow properties of blood of 60 healthy young smokers (30 female and 30 male, average age 24,4 years and 25,6 years resp.) have been compared with the flow properties of blood obtained from 60 healthy nonsmokers (30 female, average age 23,7 years and 30 male, average age 27,2 years). Statistically significant differences were found for the hematocrit values in both sexes and for the relative whole blood viscosity in the men’s group; relative whole blood viscosity in the women’s group and the other rheological parameters as relative plasma viscosity, RBC filtration rate and RBC aggregation, showed some discrepancy but…not statistically significant differences. The cause for the differences between the results presented and those of other authors might be seen in different measuring devices as well as in different selection criteria for the investigated volunteers.
Abstract: Blood viscosity, hematocrit and plasma concentrations of hemoglobin, fibrinogen, albumin and total protein were studied in 12 surgical patients (American Society of Anesthesiologists Physical Status Class I) whose pre-operative fast extended for approximately 12 hours. No significant changes were noted in any of these parameters so that a slight prolongation of the usual overnight fast did not appear to have any adverse rheological effects on these patients.
Abstract: The frequency with which blood hyperviscosity is associated with various degenerative cardiovascular disorders or with disorders which are regarded as vascular risk factors, has been underlined by numerous authors. But is there a connection between these different factors or a common determining cause which might explain the prevalence of these factors in the evolution of certain degenerative cardiovascular disorders? During the past ten years or so, numerous investigations have shown that the rheological changes in blood or in the blood cells might constitute one of the parameters the risk factors have in common. We are now fully aware that there…is a change in the rheological parameters of blood during coronary heart disease, vascular diseases and diabetes mellitus. But can we assume that at the pre-clinical stage of atheroscelrosis the risk factors all have in common a blood hyperviscosity syndrome which might foreshadow and promote the ischemic complications? It is not possible at the present time to provide a definite answer to this question.
Abstract: The annual meeting was held under the presidency of Dr. T. Azuma, Professor of Physiology, Shinshu University School of Medicine. The attendance numbered about one hundred. The meeting consisted of the following eight sections at which a total of forty three papers were presented: (1) Numerical analysis and biorheology, (2) Rheological evaluation of blood flow measurements, (3) Regulation of blood flow, (4) Rheology of cells and tissues, (5) Structure and function of blood vessel walls, (6) Pulse wave and blood vessel hemorheology, (7) Hemodynamic aspects of microcirculation, and (8) Rheology of blood. All the abstracts listed here were written…on the author’s own responsibility. The next annual meeting will be held in Tokyo under the presidency of Dr. K. Taniguchi, Associate Professor of Internal Medicine, Tokyo Medical and Dental University.