Hemorheology of pre-eclamptic patients during naftidrofuryl-treatment

Article type: Research Article

Authors: Heilmann, L.^{; *} | Hirche, H.

Affiliations: Department of Obstetric Gynecology and Department of Medical Information and Biomathmetics, University of Essen, F.R.G.

Correspondence: [*] Correspondence to Prof. Dr. med. L. Heilmann, Dept. Obstet. Gynec., Univ. of Essen, Hufelandstr. 55, 0-4300 Essen 1, FRG

Note: [] Accepted by: Editor H. Hartert

Abstract: 20 pre-eclamptic patients were treated with NAFTIDROFURYL 400 mg i.v. every day over 3 weeks. During infusion as well as before and 4 weeks after treatment rheological parameters were assessed. We found a definite improvement in erythrocyte fluidity by no change in erythrocyte aggregation and plasma viscosity. The elevated blood pressure dropped to the normal range. There were only 2 treatment failures with fetal asphyxia and subsequent cesarean section.

Keywords: Hemorheology, Pre-eclampsia, Naftidrofuryl

DOI: 10.3233/CH-1987-7503

Journal: Clinical Hemorheology and Microcirculation, vol. 7, no. 5, pp. 679-686, 1987