Red cell deformability in angina pectoris

Article type: Short Communication

Authors: Waller, D.G. | Charlesworth, P. | Roath, O.S.

Affiliations: University Departments of Clinical Pharmacology and Haematology, Southampton General Hospital, Southampton S09 4XY

Note: [] Accepted by: Editor J.A. Dormandy

Abstract: Red cell deformability was measured in 13 patients with stable angina controlled by beta-adrenoceptor antagonists and 13 controls. Filtration of leucocyte-poor blood was carried out by a modification of the Reid-Dormandy method at 37°C. No difference was found between the flow rates for blood anticoagulated with heparin, defibrinated blood or washed cells resuspended in serum when the two groups were compared. There is no evidence for impaired red cell deformability in these patients with stable angina.

Keywords: Erythrocyte deformability, ischaemic heart disease

DOI: 10.3233/CH-1985-5516

Journal: Clinical Hemorheology and Microcirculation, vol. 5, no. 5, pp. 519-522, 1985