Affiliations: [a]
Trauma Department of Orthopedics, The Affiliated Hospital of Chengde Medical University, Chengde, China
| [b]
Department of Medical Imaging, The Affiliated Hospital of Chengde Medical University, Chengde, China
Correspondence:
[*]
Corresponding author: Li-Tao Shi, Trauma Department of Orthopedics, The Affiliated Hospital of Chengde Medical University, No. 36 of Nanyingzi Street, Shuangqiao District, Chengde 067000, China. Tel.: +86 314 2279267; Fax: +86 314 2270852; E-mail: [email protected].
Abstract: OBJECTIVE:This study involved an analysis of preoperative deep vein thrombosis (DVT) incidence and changes in coagulation function among elderly patients suffering from hip fractures. The objective was to offer guidance on the prevention and management of preoperative DVT in the lower extremities of elderly individuals with hip fractures. METHODS:A total of 282 elderly individuals with a hip fracture were enrolled and divided into two groups based on the location of the fracture: femoral intertrochanteric fracture (FIF, 161 individuals) and femoral neck fracture (FNF, 121 individuals). The two groups were compared with respect to baseline characteristics, including gender, age, and comorbid chronic diseases. Furthermore, the analysis encompassed the incidence of preoperative DVT in both lower extremities, along with seven coagulation parameters and platelet count before the surgical procedure. RESULTS:There was no significant difference in baseline information between the two groups. The incidence of preoperative DVT in the FIF group was higher than that in the FNF group, along with a significantly higher percentage of patients exhibiting increased levels of D-dimer and fibrinogen/fibrin degradation products (FDPs). CONCLUSION:Preoperative hypercoagulability and a greater prevalence of DVT were observed in elderly individuals with FIF compared to individuals with FNF. This indicates that clinicians should pay attention to elderly patients with FIFs, especially those with increased D-dimer and FDP levels.
Keywords: Coagulation, deep vein thrombosis, D-dimer, elderly, femoral intertrochanteric fracture, femoral neck fracture, fibrinogen/fibrin degradation products, hip fracture
