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Article type: Research Article
Authors: Dong, Yia | Koch, Jonas B.H.b | Löwe, Axel L.b | Christen, Michaelb | Wang, Wen-Pinga | Jung, Ernst-Michaelc | Mohaupt, Markus G.d | Dietrich, Christoph F.b; *
Affiliations: [a] Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai, China | [b] Department General Internal Medicine, Hirslanden Clinics Beau-Site, Salem and Permancence, Bern, Switzerland | [c] Department of Radiology, University Medical Center Regensburg, Regensburg, Germany | [d] Department of Medicine, Teaching Hospital General Medicine Lindenhofgruppe, Berne, Switzerland
Correspondence: [*] Corresponding author: Prof. Dr. med. Christoph F. Dietrich, Department General Internal Medicine, Hirslanden Clinics Beau-Site, Salem and Permancence, Bern, Switzerland. Tel.: +41 76 440 81 50; E-mail: [email protected].
Note: [1] Supported by National Natural Science Foundation of China (Grant No. 82071942). Supported by Clinical Research Plan of SHDC (Grant No. SHDC2020CR4060). Supported by Shanghai Municipal Science and Technology Medical Guidance Project (Grant No. 18411967200).
Abstract: Dynamic contrast-enhanced ultrasound (DCE-US) enables quantification of tumor perfusion. VueBox is a platform independent external software using DICOM cine loops which objectively provides various DCE-US parameters of tumor vascularity. This review summaries its use for diagnosis and treatment monitoring of liver tumors. The existing literature provides evidence on the successful application of Vuebox based DCE-US for characterization and differential diagnosis of focal liver lesions, as well as on its use for monitoring of local ablative therapies and of modern systemic treatment in oncology.
Keywords: Dynamic contrast-enhanced ultrasound (DCE-US), liver tumors, VueBox, perfusion, quantitative
DOI: 10.3233/CH-211261
Journal: Clinical Hemorheology and Microcirculation, vol. 80, no. 4, pp. 473-486, 2022
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