Affiliations: [a] Exercise investigation and Sports Medicine, University Hospital, Angers, France
| [b] UMR CNRS 6015, INSERM 1228, Medical School, University of Angers, France
| [c] Vascular Medicine, University Hospital, Angers, France
| [d] Vascular Radiology, University Hospital, Angers, France
| [e] LAUM, UMR CNRS 6613, Groupe ESEO, Angers, France
| [f] Thoracic and Vascular Surgery, University Hospital, Angers, France
Correspondence:
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Corresponding author: P. Abraham, Laboratory of Physiology, University Hospital, Angers France. UMR INSERM
1083; CNRS6015, University of Angers, France. Tel.:+33 (0) 241 36 40 93; E-mail. [email protected].
Abstract: BACKGROUND:Non-invasive tests are still required to improve the holistic diagnostic approach of thoracic outlet syndrome (TOS). OBJECTIVES:We aimed to analyze the diagnostic accuracy of the decrease from rest oxygen pressure (DROP) index of transcutaneous oximetry (TcpO2) in TOS. METHODS:Seventy-six patients and 40 asymptomatic volunteers (Controls) were enrolled. In TOS-suspected patients, the arteriograms were investigated for the presence of≥75% stenosis. The area under receiver operating characteristics curve (AUC) analysis tested the ability of forearm TcpO2 during provocative maneuvers to discriminate patients from controls and, to predict a positive arteriographic findings in the 44 TOS-suspected patients that had an arteriography. RESULTS:The media [25/75° centile] DROP values of controls and patients were -14 [-8/-22] mmHg and -22 [-12/-42] mmHg, respectively (p for Mann-Whitney<0.02). AUC analysis showed a significant ability of TcpO2 to predict the presence of subclavian arterial compression on arteriography (AUC, 0.694). CONCLUSIONS:Although time consuming, tcpO2 is independent of the observer expertise and could be useful in TOS-suspected patients to select the patients that should undergo arteriography.
