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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: Contractile properties of striated muscle are derived from its structural organization under some assumptions about myosin crossbridges cyclic action. Well-known dynamic properties of striated muscle are given quantitatively by the suggested theory. Hill’s equations follow from the theory automatically and precisely. Calculated rates of force development and redevelopment after quick release coincide with experimental data. The theory accounts for auto-oscillations of insect flight muscles. The theory permits one to predict some new facts, for instance auto-oscillations of force developed by commonly employed frog sartorius muscles under isotonic conditions. These auto-oscillations have been registered under the predicted experimental conditions.
vol. 7, no. 3, pp. 147-170, 1971
Abstract: It is shown that neither the oil damping nor the rest pauses in the current recommended use of the thrombelastograph eliminate the measurement of the viscous part of the complex modulus. The former, however, is advantageous in preventing unwanted oscillations but the latter is best eliminated. In addition to earlier published data, we now have some 30 thrombelastograms, about half from normal subjects and half from hospital patients with various diseases. Apart from severe haemophilia, for which the equation cannot be tested, all these are adequately described by means of a simple equation already discussed in earlier papers (slightly…modified) and we conclude that the process of coagulation, which probably simply follows the polymerization of fibrin, may be described by the same kinetic equation.
vol. 7, no. 3, pp. 171-176, 1971
Abstract: Determination of the intrinsic viscosity of cattle synovial fluid, and hyaluronic acid preparations, from the data obtained with a Cannon-Manning semi-micro viscometer operated in the conventional manner (Newtonian fluid behavior and shear stress of 8.1 dynes/cm2 ) yielded results less than 6 per cent lower than when the data were treated for non-Newtonian fluid behavior and extrapolated to zero shear conditions. Hyaluronic acid from several sources, prepared by two different purification procedures, yielded values of Huggins’ constant between 0.14 and 0.17, when the calculations were made under zero shear conditions. The value of k 1 appeared to be…independent of intrinsic viscosity. The intrinsic viscosity of hyaluronic acid prepared from synovial fluid of patients with rheumatoid arthritis was about half that of hyaluronic acid prepared from normal synovial fluid.
vol. 7, no. 3, pp. 177-187, 1971