International Journal of Risk & Safety in Medicine - Volume 12, issue 3-4

Article Type: Other

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 151-156, 1999

Authors: Sanz, Emilio

Article Type: Research Article

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 157-162, 1999

Authors: Trakas, Deanna J.

Article Type: Other

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 163-166, 1999

Authors: Hussain, Samsinah Haji

Article Type: Research Article

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 167-171, 1999

Authors: Cromheecke, Manon E. | Mak, Rachel | de Mol, Bas A.J.M.

Article Type: Research Article

Abstract: Oral anticoagulation requires INR and dosage control. The availability of a portable device, called the CoaguChek® system, allows patient self‐monitoring. In this study, this self‐monitoring system is described. Then a risk analysis by means of Failure Mode & Effect Analysis and Fault Tree Analysis was applied. This systemic risk analysis revealed system weaknesses with respect to education, compliance, and technical reliability. This type of risk analysis used by the prescribing physicians can assist in recognizing increased risks of failure in the individual case as well as in analysing adverse events.

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 173-179, 1999

Authors: Froede, Emmeline | Baldwin, Steve

Article Type: Research Article

Abstract: There is a controversy about whether or not ECT is a “beneficial” treatment. Critics have emphasised the major side effects, such as disturbed memory, impaired comprehension, automatic movements, dazed facial expressions, motor restlessness, confusion, dizziness, nausea, vomiting and headaches. Supporters have argued it is a safe, reliable, effective procedure. Testimonies of eighteen ECT survivors were subjected to document analysis and content analysis, to determine the main themes/effects ECT had on recipients. The main themes identified were: fear, physical symptoms after ECT, consent, memory loss, attitudes towards ECT, degradation/dehumanisation, control, information about treatment. These data suggest that ECT is not …a form of healing, but instead the cause of more damage. Alternatives to ECT should be used more frequently, as ECT removes feelings of control. Human rights are often ignored. ECT is invasive and destructive and should be prohibited. Show more

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 181-192, 1999

Authors: Jaber, L. | , Merlob P. | Samra, Z.

Article Type: Research Article

Abstract: To determine the long‐term (3 years) response to hepatitis B vaccine, 246 full‐term healthy children, aged 10–44 months, who had been given three doses of Engerix B vaccine were studied. Children were divided into three groups by age at the time of the study: group I, 10–19 months (mean, 13.6 months) (n = 117) ; group II, 20–29 months (mean, 24.7 months) (n = 63) , and group III, 30–44 months (mean, 37.7 months) (n = 62) . The groups were compared for seroprotection rate by measuring the anti‐HBs titers (Abbott Axsym System). Anti‐HBs levels above the …presumed protection limit were found in 96.6% of group I, 95.2% of group II and 83.8% of group III. The respective geometric mean titers (GMT) were 429.6, 185.7 and 186.5 mIU/ml. There was a significant difference in seroprotection between group I and II (p = 0.0001) , group I and III (p < 0.0001) , and group I and groups II and III combined (p < 0.0001) . The specific response to the recombinant hepatitis B vaccine in this specific infant population was characterized by high immunogenicity with rates of nonresponse of 3.4–4.8% but with an early decline in antibody titer after 2 years of age. At a mean age of 35 months, 16.2% of the children had antibody levels below the presumed protection limit. Show more

Keywords: Hepatitis B vaccine, immune response, antibodies persistence

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 193-196, 1999

Article Type: Other

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 197-203, 1999

Article Type: Other

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 205-207, 1999

Article Type: Book Review

Citation: International Journal of Risk and Safety in Medicine, vol. 12, no. 3-4, pp. 209-214, 1999