Haploid evolutionary constructor: New features and further challenges

Article type: Research Article

Authors: Lashin, Sergey A.^; | Matushkin, Yury G.

Affiliations: Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

Note: [] Corresponding author: Sergey A. Lashin, Institute of Cytology and Genetics SB RAS, Lavrentiev ave. 10, Novosibirsk, Russia, 630090. Tel.: +7-383-3634969; Fax: +7-383-3331278; E-mail: [email protected].

Abstract: In this paper we consider the recent advances in methodology for modeling of prokaryotic communities evolution and new features of the software package “Haploid evolutionary constructor” (http://evol-constructor.bionet.nsc.ru). We show the principles of building complex computer models in our software tool. These models describe several levels of biological organization: genetic, metabolic, population, ecological. New features of the haploid evolutionary constructor include the modeling of gene networks and phage infections.

Keywords: Evolution modeling, simulation, prokaryotic community, gene network, phage

DOI: 10.3233/ISB-2012-0447

Journal: In Silico Biology, vol. 11, no. 3-4, pp. 125-135, 2012