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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: A mathematical model has been proposed to study the pulsatile flow of a power-law fluid through rigid circular tubes under the influence of a periodic body acceleration. Numerical solutions have been obtained by using finite difference method. The accuracy of the numerical procedure has been checked by comparing the obtained numerical results with other numerical and analytical solutions. It is found that the agreement between them is quite good. Interaction of non-Newtonian nature of fluid with the body acceleration has been investigated by using the physiological data for two particular cases (coronary and femoral arteries). The axial velocity, fluid acceleration,…wall shear stress and instantaneous volume flow rate have been computed and their variations with different parameters have been analyzed. The following important observations have been made: (i) The velocity and acceleration profiles can have more than one maxima, this is in contrast with usual parabolic profiles where they have only one maximum at the axis. As n increases, the maxima shift towards the axis; (ii) For the flow with no body acceleration, the amplitude of both, wall shear and flow rate, increases with n, whereas for the flow with body acceleration, the amplitude of wall shear (flow rate) increases (decreases) as n increases; (iii) In the absence of body acceleration, pseudoplastic (dilatant) fluids, with low frequency pulsations, have higher (lower) value of maximum flow rate Qmax than Newtonian fluids, whereas for high frequencies, opposite behavior has been observed; for flow with body acceleration pulsations gives higher (lower) value of Qmax for pseudoplastic (dilatant) fluids than Newtonian fluids.
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Keywords: Power-law fluid, Body acceleration, Pulsatile flow, Finite difference method
DOI: 10.3233/BIR-1990-27510
Citation: Biorheology,
vol. 27, no. 5, pp. 747-758, 1990
Abstract: The stress relaxation of the cell wall of pea plants was measured and viscoelastic parameters were obtained according to the stress- relaxation analysis developed by Yamamoto et al. (Plant & Cell Physiol. 1970). The creep process of the cell wall was simulated by a numerical integration using stress-relaxation parameters, because the direct conversion of the stress relaxation process to the creep is impractical. In the conversion, a personal computer was programmed for the Maxwell viscoelastic model with a compiler language. Cell wall creep was measured with a specially constituted apparatus and compared with that calculated by the simulation process. The…results suggested that the creep can be reproduced by a computer simulation using the stress-relaxation parameters. Both creep and stress-relaxation properties of plant cell walls can be analyzed by using a single model.
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Abstract: We measured the electric current dependence of sedimentation curves of swine erythrocytes in a saline solution at the volume fraction of erythrocytes H = 0.091 and 0.220. The sedimentation curve fitted well to the exponential type equation ı = a [ 1 − exp ( − b t ) ] at the upward initial electric current I 0 = 0.50 mA , 1.01 mA and 1.50 mA, where ı is the length of the medium layer at time t ,…and a and b are phenomenological parameters. The initial slope v 0 of sedimentation curve was enhanced from 0.68 mm/hr at I 0 = 0 mA to 2.85 mm/hr, 3.87 mm/hr and 5.50 mm/hr at I 0 = 0.50 mA , 1.01 mA and 1.50 mA, respectively, for H = 0.220 . We also made sedimentation measurements of erythrocytes in their own plasma at H = 0.220 and 0.316. Sedimentation curves coincided with the sigmoidal type equation ı = ı ∞ / { 1 + ( t 50 / t ) β } at I 0 = 0 mA and 0.50 mA, where ı ∞ is ı at t → ∞ , t 50 is the time when the plasma level falls to ı ∞ / 2 and β is a constant. The maximum slope v max of sedimentation curve increased from 13.29 mm/hr at I 0 = 0 mA to 18.65 mm/hr at I 0 = 0.50 mA for H = 0.220 .
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Keywords: Erythrocyte sedimentation rate, swine blood, saline solution, plasma, DC electric field
DOI: 10.3233/BIR-1990-27512
Citation: Biorheology,
vol. 27, no. 5, pp. 769-777, 1990
Abstract: Blood viscosity in normal adults was measured in glass tubes with diameters of 50, 100 and 500 μ m for a wide range of adjusted feed hematocrits (15-70%). Blood viscosity decreased at each of the adjusted feed hematocrits when going from a 500-μ m tube to a 50-μ m tube. The viscosity reduction increased with increasing hematocrit. The steepness in the hematocrit-viscosity curves decreased with decreasing tube diameter. Erythrocyte transport efficiency (hematocrit / blood viscosity) was calculated to estimate the optimal hematocrit for oxygen transport. Optimal hematocrit averaged 38% in 500-μ m tubes, 44% in 100-μ m tubes and 51%…in 50-μ m tubes. Our results suggest that the strong Fåhraeus-Lindqvist effect at high hematocrits may help to maintain oxygen transport in polycythemic patients as long as the driving pressure is sufficient.
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Keywords: Blood viscosity, hematocrit, oxygen transport, red blood cell (RBC)
DOI: 10.3233/BIR-1990-27513
Citation: Biorheology,
vol. 27, no. 5, pp. 779-788, 1990