Affiliations: [a] Department of Biological & Chemical Engineering, Faculty of Technology, Gunma University, Kiryu, Gunma 376, Japan | [b] Research Center of Bioengineering, Chong-qing University, Chong-qing, Sichuan 630044, China | [c] National Cardiovascular Center Research Institute, Suita, Osaka 565, Japan
Note: [*] On leave of absence from Research Center of Bioengineering, Chong-qing University, Chong-qing, Sichuan 630044, China
Note: [] Accepted by: Editor E. Fukada
Abstract: We measured the electric current dependence of sedimentation curves of swine erythrocytes in a saline solution at the volume fraction of erythrocytes H=0.091 and 0.220. The sedimentation curve fitted well to the exponential type equation
ı=a[1−exp(−bt)]
at the upward initial electric current I0=0.50mA, 1.01 mA and 1.50 mA, where ı is the length of the medium layer at time t, and a and b are phenomenological parameters. The initial slope v0 of sedimentation curve was enhanced from 0.68 mm/hr at I0=0mA to 2.85 mm/hr, 3.87 mm/hr and 5.50 mm/hr at I0=0.50mA, 1.01 mA and 1.50 mA, respectively, for H=0.220. We also made sedimentation measurements of erythrocytes in their own plasma at H=0.220 and 0.316. Sedimentation curves coincided with the sigmoidal type equation
ı=ı∞/{1+(t50/t)β}
at I0=0mA and 0.50 mA, where ı∞ is ı at t→∞, t50 is the time when the plasma level falls to ı∞/2 and β is a constant. The maximum slope vmax of sedimentation curve increased from 13.29 mm/hr at I0=0mA to 18.65 mm/hr at I0=0.50mA for H=0.220.
Keywords: Erythrocyte sedimentation rate, swine blood, saline solution, plasma, DC electric field
DOI: 10.3233/BIR-1990-27512
Journal: Biorheology, vol. 27, no. 5, pp. 769-777, 1990
