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Biorheology is an international interdisciplinary journal that publishes research on the deformation and flow properties of biological systems or materials. It is the aim of the editors and publishers of
Biorheology to bring together contributions from those working in various fields of biorheological research from all over the world. A diverse editorial board with broad international representation provides guidance and expertise in wide-ranging applications of rheological methods to biological systems and materials.
The aim of biorheological research is to determine and characterize the dynamics of physiological processes at all levels of organization. Manuscripts should report original theoretical and/or experimental research promoting the scientific and technological advances in a broad field that ranges from the rheology of macromolecules and macromolecular arrays to cell, tissue and organ rheology. In all these areas, the interrelationships of rheological properties of the systems or materials investigated and their structural and functional aspects are stressed.
The scope of papers solicited by
Biorheology extends to systems at different levels of organization that have never been studied before, or, if studied previously, have either never been analyzed in terms of their rheological properties or have not been studied from the point of view of the rheological matching between their structural and functional properties. This biorheological approach applies in particular to molecular studies where changes of physical properties and conformation are investigated without reference to how the process actually takes place, how the forces generated are matched to the properties of the structures and environment concerned, proper time scales, or what structures or strength of structures are required.
Biorheology invites papers in which such 'molecular biorheological' aspects, whether in animal or plant systems, are examined and discussed. While we emphasize the biorheology of physiological function in organs and systems, the biorheology of disease is of equal interest. Biorheological analyses of pathological processes and their clinical implications are encouraged, including basic clinical research on hemodynamics and hemorheology.
In keeping with the rapidly developing fields of mechanobiology and regenerative medicine,
Biorheology aims to include studies of the rheological aspects of these fields by focusing on the dynamics of mechanical stress formation and the response of biological materials at the molecular and cellular level resulting from fluid-solid interactions. With increasing focus on new applications of nanotechnology to biological systems, rheological studies of the behavior of biological materials in therapeutic or diagnostic medical devices operating at the micro and nano scales are most welcome.
Abstract: Longitudinal motility of the small intestine is an instance of smooth muscle activity. Its correlation with the characteristics of the electrical slow wave of the intestine is of fundamental importance in understanding the behavior of the intestine and its functions. From a fluid-mechanical point of view, the small intestine is an organ which acts on the chyme in its interior to generate several flow processes which are deterministically related to the wall motion. In this paper, a simple model for the longitudinal motion of the intestinal wall is formulated and applied to predict the behavior of the intestine in a…particular experimental situation. Theoretical results and data from in vitro experiments in which purely longitudinal motility was obtained show a satisfactory agreement.
vol. 12, no. 6, pp. 369-376, 1975
Abstract: The effects of drag reducing polymers on blood hemolysis during extracorporeal circulation with a prototype roller pump reveal several polymers of both the modified polysaccharide and cellulose types to be capable of effecting significant decreases in red cell breakage at concentrations between 200–500 ppm. First normal stress measurements on dilute solutions of these polymers suggest that the phenomenon may correlate with level of fluid viscoelasticity.
vol. 12, no. 6, pp. 377-382, 1975
Abstract: A non-linear viscoelastic constitutive equation is proposed as a model for blood. The model allows normal stress effects which are observed to occur in viscoelastic fluids but not included in most rheological models for blood. The shear thinning nature of the model is illustrated by its application in circular Couette flow. A two-dimensional channel flow problem is included to show that a blunted profile can be predicted. Finally, application to the Couette flow viscometer problem shows that a stress overshoot is predicted by the viscoelastic model proposed without the need for a postulate of a cell-free layer.
vol. 12, no. 6, pp. 383-389, 1975
Abstract: Non destructive creep compliance tests have been used to investigate the effects of tetracycline antibiotics on the physical properties of human bronchial mucus in vitro . Oxytetracycline, tetracycline, chlortetracycline and demethylchlortetracycline resulted in an increase in consistency of the mucus which was produced by homogenisation of the gel phase. In contrast pyrrolidinomethyltetracycline reduced the residual shear viscosity (η 0 ) and increased the instantaneous shear compliance (J 0 ). Neither the hydrogen ion concentration of the antibiotic solutions nor the chelation of calcium within the gel could be shown to account for the observed results. It is concluded that tetracycline-glycoprotein…interactions may provide a possible explanation of the reported changes.
vol. 12, no. 6, pp. 391-395, 1975
Abstract: Changes in the mechanical properties of animal tissues with time after death have been frequently observed, and descriptions of rigor mortis for example are numerous. Most previous accounts of mechanical changes in tissues during the life-to-death transition, however, are qualitative. Measurements of dynamic shear compliance vs dead time at room temperatures are reported here for cow gluteal muscle, several samples of rabbit and human cancellous bone, and dog intervertebral disks. In all cases an abrupt second-order transition is observed in one or both components of the audiofrequency complex shear compliance, J ∗ = J ′…− i J ″ at 5–6 hr after death; this is considered to be an indication of the life-to-death transition in animal tissues.
vol. 12, no. 6, pp. 397-408, 1975