Affiliations: [a] Department of Pedodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, India
| [b] Department of Periodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, India
Correspondence:
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Corresponding author: Sourabh Joshi, Department of Pedodontics, Rural Dental College, Pravara Institute of Medical Sciences, Loni, India. E-mail: [email protected].
Abstract: Enamel Matrix Derivatives (EMD) is a novel biomaterial that has been discovered in the late ’90 s and has found numerous uses in the field of periodontics. It is mainly used in areas that require natural regeneration and healing. It has found applications in other branches of dentistry, such as; wound healing, regenerative procedures, endodontics, pedodontics, and others. It mainly consists of amelogenins and other proteins such as amelin, enamelin, tufetelin etc. It is known to increase cementogenesis and improve periodontal attachment. The amount of research done on this product is very little and very scattered. The maximum amount of research has been done regarding its use in periodontic surgery and other related procedures since it had been initially discovered as a material that would increase periodontal attachment. Given its various biological properties, it is safe to say that it has the potential to succeed in other branches. Our review, therefore, aims to collect and present the research performed and ongoing research potential regarding EMD products, which are now available in a gel-based form known as Emdogain.
