Fragment-Based Molecular Design of New Competitive Dengue Den2 Ns2b/Ns3 Inhibitors from the Components of Fingerroot (Boesenbergia rotunda)

Article type: Research Article

Authors: Frimayanti, Neni | Zain, Sharifuddin M. | Lee, Vannajan Sanghiran^; | Wahab, Habibah A. | Yusof, Rohana | Rahman, Noorsaadah Abd.

Affiliations: Department of Chemistry, Faculty of Science, University of Malaya Lembah Pantai, Kuala Lumpur, Malaysia | Computational Simulation and Modeling Laboratory, Department of Chemistry and Center for Innovation in Chemistry, Chiang Mai University, Bangkok, Thailand | Pharmaceutical Design and Simulation Laboratory, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia | Department of Molecular Medicine, Faculty of Medicine, University Malaya, Kuala Lumpur, Malaysia

Note: [] Corresponding author. Tel.: +603 79674254; Fax: +603 79674193; E-mail: [email protected]

Keywords: Fragment-based, Docking, Dengue DEN2 NS2B/NS3, Boesenbergia rotunda

DOI: 10.3233/ISB-2012-0442

Journal: In Silico Biology, vol. 11, no. 1-2, pp. 29-37, 2012