Abstract: Alternative splicing of mRNA allows many gene products with
different functions to be produced from a single coding sequence. Exon skipping
is the most commonly known alternative splicing mechanism. A comprehensive
database of alternative splicing by exon skipping is made available for the
human genome data. 1,229 human genes are identified to exhibit alternative
splicing by exon skipping.
Keywords: alternative splicing, eukaryotic gene structure, exon skipping, multiple splice variants, protein isoforms, protein diversity, skipping patterns, genome wide splicing, full length cDNA sequences, tissue specificity, computational analysis, database