Deriving an Ontology for Human Gene Expression Sources from the CYTOMER® Database on Human Organs and Cell Types

Issue title: ONTOLOGY WORKSHOP GÖTTINGEN 2004

Article type: Research Article

Authors: Michael, Holger | Chen, Xin | Fricke, Ellen | Haubrock, Martin | Ricanek, Remko | Wingender, Edgar^;

Affiliations: Department of Bioinformatics, Faculty of Medicine, Georg August University Göttingen, Goldschmidtstr. 1, D-37077 Göttingen, Germany | The National Laboratory of Protein Engineering and Plant Genetic Engineering, College of Life Sciences, Peking University, Beijing 100871, P.R. China | BIOBASE GmbH, Halchtersche Str. 33, D-38304 Wolfenbüttel, Germany

Note: [] Corresponding author. Tel.: +49 551 39 14918; Fax: +49 551 39 14914; E-mail: [email protected]

Abstract: CYTOMER® is a relational database of organs/tissues, cell types, physiological systems and developmental stages that currently focuses on the human system. From this database, we have derived an ontology for anatomical and morphological structures for the human organism which includes all embryonic stages and the cell types constituting these structures. The ontology has been transferred to the OWL format and is freely available for download at http://cytomer.bioinf.med.uni-goettingen.de.

Keywords: ontologies, human developmental stages, gene expression sources, relational database system, OWL, internet resource

Journal: In Silico Biology, vol. 5, no. 1, pp. 61-66, 2005