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Article type: Research Article
Authors: Sakharkar, Kishore R. | Chow, Vincent T.K.
Affiliations: BioInformatics Institute, Singapore | Human Genome Laboratory, Department of Microbiology, Faculty of Medicine, National University of Singapore, Kent Ridge, Singapore 117597. Tel.: +65 6874 6200; Fax: +65 6776 6872; E-mail: [email protected]
Note: [] Corresponding author
Abstract: With the complete sequencing of multiple genomes, there have been extensions in the methods of sequence analysis from single gene/protein-based to analyzing multiple genes and proteins simultaneously. Therefore, there is a demand for user-friendly software tools that will allow mining of these enormous datasets. PPD is a WWW-based database for comparative analysis of protein lengths in completely sequenced prokaryotic and eukaryotic genomes. PPD's core objective is to create protein classification tables based on the lengths of proteins by specifying a set of organisms and parameters. The interface can also generate information on changes in proteins of specific length distributions. This feature is of importance when the user's interest is focused on some evolutionarily related organisms or on organisms with similar or related tissue specificity or life-style. PPD is available at: PPD Home.
Keywords: protein length distribution, proteome, bioinformatics, genomics, obligatory intracellular parasites, genome, size, reduction, database, distribution, profile, classification, COG, KEGG, amino acid, composition, evolution, gene, organism life-style
Journal: In Silico Biology, vol. 4, no. 2, pp. 219-223, 2004
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