Mass spectrometry of some arylidene thioxobenzyl or thioxobiphenyloxoethyl thiazolidinone compounds

Article type: Research Article

Authors: Guarda, V.L.M. | Bosso, C. | Galdino, S.L. | Albuquerque, J.F.C. | Lima, M.C.A. | Silva, J.B.P. | Leite, L.F.C. | Pitta, I.R.

Affiliations: Grupo de Pesquisa do Laboratório de Planejamento e Síntese de Fármacos, Universidade Federal de Pernambuco, Cidade Universitária, CEP 50670‐901 Recife, Brasil | Centre de Recherches sur les Macromolécules Végétales ‐ CERMAV ‐ CNRS, BP 53X, 38041 Grenoble cédex, France

Abstract: This paper reports the results of a comparative study of the electron impact mass spectrometry data for a series of previously synthetized 5‐arylidene‐3‐(4‐chloro‐benzyl)‐4‐thioxo‐thiazolidin‐2‐one, and 5‐arylidene‐3‐(2‐biphenyl‐4‐yl‐2‐oxo‐ethyl)‐4‐thioxo‐thiazolidin‐2‐one derivatives. Theoretical calculations of molecular mechanics, MOPAC‐AM1, were used to explain the fragmentations observed.

Keywords: Mass spectra, thiazolidinones

Journal: Spectroscopy, vol. 18, no. 4, pp. 613-619, 2004