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Issue title: Visual Plasticity, Restoration and Rehabilitation
Article type: Research Article
Authors: Gaillard, Frédéric | Domballe, Linda
Affiliations: Institut de Physiologie et Biologie Cellulaires (UMR 6187 CNRS), Université de Poitiers, Poitiers, France | Laboratoire Homeostasie Cellulaire et Pathologie (EA 3842), Université de Limoges, Limoges, France
Note: [] Address for correspondence: Dr. F. Gaillard, Institut de Physiologie et Biologie Cellulaire, Université de Poitiers, Faculté des Sciences, 40 avenue du Recteur Pineau, F-86022 Poitiers, France. Tel.: +33 549 453 853; Fax: +33 549 454 014; E-mail: [email protected]
Abstract: During the past three decades, many studies have examined the capacity of embryonic neural grafts (dissociated cells or tissue blocks) to restore lost functions following various damages to the adult mammalian brain. Only very few focused on the visual system even if it is the optimal system to examine the potential of embryonic neural grafts in repairing point-to-point networks. Collectively, these studies show that, within limits, homologous sheets of fetal tissue grafted in the occipital cortex of adult rodents integrate into the host visual circuitry and are physiologically active.
Keywords: Embryonic cells, transplantation, adult brain, visual cortex, rodent
Journal: Restorative Neurology and Neuroscience, vol. 26, no. 4-5, pp. 267-277, 2008
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