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Article type: Research Article
Authors: Widdig, Walter; * | Pleger, Burkhard | Rommel, Oliver | Malin, Jean-Pierre | Tegenthoff, Martin
Affiliations: Department of Neurology, Ruhr-University BG-Hospital Bergmannsheil, D-44789 Bochum, Germany
Correspondence: [*] Address for correspondence: Walter Widdig, PhD, Department of Neurology, Ruhr-University BG-Hospital Bergmannsheil, Bürkle-de-la-Camp-Platz 1, D-44789 Bochum, Germany. Tel.: +49 234 302 3515; Fax: +49 234 330734; E-mail: [email protected]
Abstract: Cortical visual disturbances can occur after traumatic or ischemic brain lesion. Patients mostly suffer from hemianopia. Different treatment approaches in patients with hemianopia are being debated with respect to their effectiveness. For more severely disabled patients with cortical blindness or residual rudimentary vision (RRV) no systematic therapeutic approaches have been reported. In a case study the positive effects of a recently developed repetitive photic stimulation therapy in a patient with RRV after a bioccipital ischemic infarction are presented. The application of this new therapy over several months, supported by treatment with amphetamines led to a statistically significant improvement of different visual functions and a reoccurrence of visual abilities important in daily life. The pathophysiological basis and possible neurorehabilitative consequences that arise from these results are discussed with respect to similar findings in animal experiments.
Keywords: cortical blindness, tachistoscopic stimulation, photic stimulation, cortical plasticity, treatment of visual disorders
DOI: 10.3233/NRE-2003-18307
Journal: NeuroRehabilitation, vol. 18, no. 3, pp. 227-237, 2003
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