Affiliations: Department of Physical Medicine and Rehabilitation, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey
Correspondence:
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Corresponding author: Bilge Kesikburun, Department of Physical Medicine and Rehabilitation, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Kazım Karabekir Boulevard, Aslanbey Street, İskitler, Ankara, Turkey. Tel.: +90 312 341 03 00; Fax: +90 312 318 66 90; E-mail:[email protected]
Abstract: BACKGROUND: Protracted Febrile Myalgia is a rare form of vasculitis
that is diagnosed in patients with Familial Mediterranean Fever. OBJECTIVE: To present a case with Familial Mediterranean and
Anklosing Spondylitis on anti-TNF therapy for three years, who developed
protracted febrile myalgia syndrome. METHODS: Case report. RESULTS: A 35-year-old woman with known Familial Mediterranean
Fever and Anklosing Spondylitis for 3 years presented with fever, diarrhea,
intermittent abdominal pain and severe diffuse muscular pain lasting for two
weeks. The patient was investigated for any infection focus. The patient was
diagnosed as having Protracted Febrile Myalgia four weeks after the onset of
the symptoms. Prednisolone 1 mg/kg per day was applied. Her fever and muscle
pain resolved within 48 hours. CONCLUSION: The coexisting Ankylosing Spondylitis disease and the
use of anti-TNF treatment in patients with Familial Mediterranean Fever
could be a confounding factor for the investigation of fever. Steroid
therapy has a dramatic response.
