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Issue title: Workshop: Breaking Symmetry in Haemodynamics, London, UK, 23–24 April 2001
Article type: Research Article
Authors: Lu, Yiling | Lu, Xiyun | Zhuang, Lixian | Wang, Wen;
Affiliations: Department of Mechanics and Mechanical Engineering, University of Science and Technology of China, Hefei, PR China | Medical Engineering Division, Department of Engineering, Queen Mary, University of London, London, UK
Note: [] Address for correspondence: Dr. Wen Wang, Medical Engineering Division, Department of Engineering, Queen Mary, University of London, London E1 4NS, UK. Tel.: +44 20 7882 5369; Fax: +44 20 8983 1007; E‐mail: [email protected].
Abstract: Non‐planarity in blood vessels is known to influence arterial flows and wall shear stress. To gain insight, computational fluid dynamics (CFD) has been used to investigate effects of curvature and out‐of‐plane geometry on the distribution of fluid flows and wall shear stresses in a hypothetical non‐planar bifurcation. Three‐dimensional Navier–Stokes equations for a steady state Newtonian fluid were solved numerically using a finite element method. Non‐planarity in one of the two daughter vessels is found to deflect flow from the inner wall of the vessel to the outer wall and to cause changes in the distribution of wall shear stresses. Results from this study agree to experimental observations and CFD simulations in the literature, and support the view that non‐planarity in blood vessels is a factor with important haemodynamic significance and may play a key role in vascular biology and pathophysiology.
Keywords: Wall shear stress, non‐planar bifurcation, CFD modeling
Journal: Biorheology, vol. 39, no. 3-4, pp. 431-436, 2002
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