Anticoagulants and erythrocyte filterability

Issue title: New Methods in Biorheology. Proceedings of the International Symposium held in Nancy, France, 17–18 August 1983. A Satellite Symposium of the Fifth International Congress of Biorheology

Guest editors: J.F. Stoltz and E. Puchelle

Article type: Research Article

Authors: Stuart, J.^{; *} | Lucas, G.S. | Caldwell, N.M. | Kenny, M.W. | Meakin, M. | Aillaud, M.F. | Juhan-Vague, I.

Affiliations: Department of Haematology, The Medical School, University of Birmingham, Birmingham Bl5 2TJ, UK and Laboratoire Central d’Hématologie, Hôpital de la Timone, 13385 Marseille, France

Correspondence: [*] Correspondence to Professor J. Stuart, Birmingham.

Abstract: Positive-pressure and initial-flow-rate (Hémorhéomètre) filtration systems were used to study the deformability of erythrocytes from whole blood stored in EDTA or heparin. When all contaminating platelets and leucocytes were removed from the erythrocyte suspension there was no significant anticoagulant effect on erythrocyte filtration. Blood may therefore be stored in K2EDTA (1.5 mg/ml blood) or lithium heparin (15 IU/ml blood) for up to 6 hours at room temperature prior to measurement of erythrocyte filterability.

Keywords: Rheology, Anticoagulants, Erythrocyte deformability

DOI: 10.3233/BIR-1984-23S149

Journal: Biorheology, vol. 23, no. s1, pp. 279-281, 1984