A new device for the routine measurement of erythrocyte deformability

Issue title: New Methods in Biorheology. Proceedings of the International Symposium held in Nancy, France, 17–18 August 1983. A Satellite Symposium of the Fifth International Congress of Biorheology

Guest editors: J.F. Stoltz and E. Puchelle

Article type: Research Article

Authors: Roggenkamp, H.G.^a | Jung, F.^b | Schneider, R.^c | Kiesewetter, H.^b

Affiliations: [a] Abteilung Augenheilkunde der RWTH Aachen, Goethestr. 27-29, D-5100 Aachen | [b] Abteilung für Klinische Haemostaseologie und Transfusionsmedizin, Universität des Saarlandes, 0-6650 Homburg / Saar, West-Germany | [c] Abteilung Neurologie der RWTH Aachen, Goethestr. 27-29, 0-5100 Aachen

Abstract: We present a device for the routine measurement of the deformability of individual red blood cells, the so called Single-Erythrocyte-Rigidometer (SER). The time required for individual erythrocytes to traverse a single pore membrane (pore diameter = 5 μm, pore length = 25 μm) is taken as an index of red cell deformability. For example we present the results from patients with insult, polyneuropathy and morbus binswanger. Compared to the results of erythrocytes of healthy probands a significantly increased rigidity of the RBC of the patients can be diagnosed.

Keywords: RBC-Deformability, Single-Erythrocyte-Rigidometer(SER, Single Pore

DOI: 10.3233/BIR-1984-23S141

Journal: Biorheology, vol. 23, no. s1, pp. 241-243, 1984