Methods to study rheological properties of blood during clotting

Issue title: New Methods in Biorheology. Proceedings of the International Symposium held in Nancy, France, 17–18 August 1983. A Satellite Symposium of the Fifth International Congress of Biorheology

Guest editors: J.F. Stoltz and E. Puchelle

Article type: Research Article

Authors: Fukada, Eiichi | Sugiura, Yoshihiko | Date, Munehiro | Kaibara, Makoto

Affiliations: The Institute of Physical and Chemical Research, Wako, Saitama 351, Japan

Abstract: In vitro rheological studies on clotting of fibrinogen solution, plasma and blood are reviewed. Multiple viscoelastorecorder (MVER) and viscoelastorecorder (VER) were developed for determining the dynamic rigidity modulus (G′) and loss modulus (G″) during clotting. The effect of some parameters on clotting and the properties of fibrin clot are discussed. The parameters include measuring frequency, measuring shear strain and surface coating of measuring cell. The change of dynamic rigidity during clotting was compared between normal plasma and plasma from patient with Glanzmann’s disease. By detecting the stress at the higher harmonic frequency, the non-linear terms of G′ and G″ were determined.

Keywords: blood clotting, viscoelasticity, fibrinogen, platelet and plasma

DOI: 10.3233/BIR-1984-23S103

Journal: Biorheology, vol. 23, no. s1, pp. 9-14, 1984