A biological probe for analyzing shear in turbulent flow

Issue title: Perspectives in Biorheology. Festschrift for A.L. Copley

Guest editors: Alexander Silberberg

Article type: Research Article

Authors: Charm, S.E. | Wong, B.L.

Affiliations: Tufts University School of Medicine Boston, Massachusetts

Note: [] Invited by: Editor A. Silberberg

Abstract: Biological materials in flow are found to be degraded in flow through shear. Turbulent flow results in greater loss than streamline flow. It is possible to correlate a shear factor associated with flow with the Reynolds number. This preliminary study was carried out with lysozyme and covered a narrow range of Reynolds number. The plot of a shear factor vs the Reynolds number should be universal and independent of the material used to derive it. With this plot, it should be possible to determine the amount of inactivators expected for a material undergoing turbulent flow.

Keywords: Turbulence, shear, biomaterial, inactivation, Reynolds number, enzyme, lysozyme

DOI: 10.3233/BIR-1981-183-627

Journal: Biorheology, vol. 18, no. 3-6, pp. 653-657, 1981