Role of stress concentration in arterial walls in atherogenesis¹

Article type: Research Article

Authors: Niimi, Hideyuki

Affiliations: National Cardiovascular Center, Research Institute, Suita, Osaka, 565, Japan

Note: [1] Third International Congress of Biorheology

Note: [] Accepted by: Editor S. Oka

Abstract: In order to explain the pathogenesis of regional atherosclerotic plaques, the solid-dynamical force is emphasized. The regi.onal stress and deformation in the arterial wall near the ostium hole for branching is analyzed within the framework of shallow shell approximation. A high concentration in the stress and deformation is demonstrated. Following making a theoretical explanation how the regional stress and deformation could be involved for the transport of molecules across the endothelium, a new factor of the regional initiation of atherosclerosis is proposed.

DOI: 10.3233/BIR-1979-16311

Journal: Biorheology, vol. 16, no. 3, pp. 223-230, 1979