Changes of the total antioxidative status of blood cells in the
progression of stomach and large bowel cancers in patients subjected to primary
radical treatment
Issue title: The Proceedings of the 3rd International
Conference on Food Factors (ICoFF 03)
Affiliations: Military Clinical Hospital, 1-3 Wrocławska str.,
30-901 Kraków, Poland | Academy of Physical Education, 78 Al. Jana Pawła
II, 31-571 Kraków, Poland | Military Institute of Hygiene and Epidemiology, 4
Kozielska str., 01-163 Warszawa, Poland | Jagiellonian University, Medical College, 7 Kopernika
str., 31-034 Kraków, Poland | H. Dietl Hospital, 1 Skarbowa, 31-121 Kraków,
Poland | Clinic of Oncological Surgery of the Oncology
Institute, 11 Garncarska, 31-115 Kraków, Poland
Abstract: The analysis included 53 patients (32 men and 21 women) aged 43 to
66 years, who were subjected to radical treatment (surgical or combined)
because of stomach (22 patients) or large bowel (31 patients) cancer. All the
patients were included in the same model of control examinations, which
considered evaluation of the erythrocytes TAS and of the Ca19-9, CEA and AFP
concentrations in serum. It was confirmed that in all the patients in whom the
recurrence and/or the dissemination occurred of the cancer, the average
erythrocytes TAS value increased 5.5 times by comparison with the period before
progression and 7 times in comparison with the patients without recurrence
and/or dissemination of the cancer. Moreover it was shown that statistically
significantly higher TAS values were associated with the progression of the
large bowel cancer in comparison with the stomach cancer and that the blood
cells TAS positively correlated with the changes of the Ca19-9, CEA and AFP
concentrations in patients with progression of the cancer after radical
treatment.
Keywords: total antioxidative status (TAS), stomach cancer, large bowel cancer, neoplasm progression
Journal: BioFactors, vol. 22, no. 1-4, pp. 75-78, 2004
