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NeuroRehabilitation, an international, interdisciplinary, peer-reviewed journal, publishes manuscripts focused on scientifically based, practical information relevant to all aspects of neurologic rehabilitation. We publish unsolicited papers detailing original work/research that covers the full life span and range of neurological disabilities including stroke, spinal cord injury, traumatic brain injury, neuromuscular disease and other neurological disorders.
We also publish thematically organized issues that focus on specific clinical disorders, types of therapy and age groups. Proposals for thematic issues and suggestions for issue editors are welcomed.
Article Type: Research Article
Abstract: We investigated red nucleus (RN) changes in patients with a cerebral infarct, using diffusion tensor imaging (DTI). Forty-nine consecutive stroke patients with pyramidal tract(PT) injury (mean age, 62.1 years; range, 41 to 75) and 46 age-matched normal healthy control subjects (mean age, 58.9 years; range, 41 to 75) with no history of neurologic disease were recruited. DTI was performed using a 1.5-T system during the early stage, after cerebral infarct (8–l21 days after onset). DTIs were acquired using a sensitivity-encoding head coil at 1.5 T. We measured fractional anisotropies (FAs) and apparent diffusion coefficients (ADCs) of RNs in the upper …midbrain, and assessed the motor function of affected extremities. Mean FA of RNs in affected hemispheres was higher than in unaffected hemispheres (P < 0.05), however, no difference was observed between the unaffected control hemispheres (P > 0.05). However, mean ADC values of RNs were no different between control hemispheres and a patient's affected and unaffected hemispheres (P > 0.05). It appears that RN in affected hemispheres show elevated levels of neuronal activity during the early stage in patients with a corona radiata infarct, which suggests that RNs in affected hemispheres are used to compensate for PT injury. Show more
Keywords: Diffusion tensor imaging, stroke, red nucleus, hemiparesis, pyramidal tract
Citation: NeuroRehabilitation, vol. 27, no. 4, pp. 373-377, 2010
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